×îÐÂÂé¶¹ÊÓÆµ

Health

A dramatic rethink of Parkinson’s offers new hope for treatment

Mounting evidence suggests there might be two separate types of the world’s fastest-growing neurological condition. Can this fresh understanding lead to much-needed new treatments?

By Alexandra Thompson

21 April 2025

×îÐÂÂé¶¹ÊÓÆµ. Science news and long reads from expert journalists, covering developments in science, technology, health and the environment on the website and the magazine.

Sunnu Rebecca Choi

Per Borghammer’s “aha” moment came nearly 20 years ago. The neuroscientist was reading a paper from researchers who were examining whether REM sleep behaviour disorder (RBD), a condition that causes people to act out their dreams and is often found in people who later develop Parkinson’s disease, could be an early form of the neurological condition.

Rather than starting with the brain, however, the team instead looked for nerve cell loss in the heart. Though Parkinson’s is historically associated with nerve cell depletion in the brain, it also affects neurons in the heart that manage autonomic functions…

Sign up to our weekly newsletter

Receive a weekly dose of discovery in your inbox! We'll also keep you up to date with ×îÐÂÂé¶¹ÊÓÆµ events and special offers.

Sign up

To continue reading, today with our introductory offers

or

Existing subscribers

Sign in to your account
Piano Exit Overlay Banner Mobile Piano Exit Overlay Banner Desktop